Product Description:
N,N''-Carbonyldiimidazole is a reagent used for peptide synthesis, forming amide, ester, and anhydride bonds. It is a white crystalline solid, highly reactive with moisture.
Applications & Uses:
CAS#:
530-62-1
SYNONYM:
CDI;1,1'-Carbonyldiimidazole;Carbonyldiimidazole
FORMULA:
C7H6N4O
PRODUCT TYPE:
HAZARD:
Corrosive
CATEGORIES:
Organic Intermediate
,
Intermediates
,
Pharmaceutical
N,N’-Carbonyldiimidazole, also known as CDI, is a versatile reagent widely utilized in organic synthesis. This crystalline compound, characterized by its white to off-white appearance, serves as an efficient dehydrating agent, promoting the formation of amides, esters, and anhydrides from carboxylic acids. Its role in peptide synthesis is particularly noteworthy, as CDI facilitates the coupling of amino acids, enhancing the efficiency and yield of peptide bond formation. Beyond peptide synthesis, N,N’-Carbonyldiimidazole finds applications in pharmaceutical development, contributing to the creation and modification of drug molecules. It is also employed in the preparation of heterocyclic compounds, making it an indispensable tool in the chemical industry. With its ability to enhance chemical reactions without the need for additional catalysts, CDI is an essential reagent in the toolkit of chemists and researchers focused on innovative synthetic pathways.