Product Description:
N-(3-Dimethylaminopropyl)-N''-ethylcarbodiimide is commonly used as a coupling agent in peptide synthesis and in the activation of carboxyl groups.
Applications & Uses:
CAS#:
25952-53-8
SYNONYM:
EDC;EDC.HCl;EDC hydrochloride;1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide
FORMULA:
C8H17N3
PRODUCT TYPE:
HAZARD:
Irritant
CATEGORIES:
Organic Intermediate
,
Intermediates
N-(3-Dimethylaminopropyl)-N''-ethylcarbodiimide, often abbreviated as EDC or EDAC, is a highly efficient water-soluble carbodiimide reagent widely utilized in the biochemical and pharmaceutical industries. Its chemical structure, characterized by a reactive carbodiimide group, makes it an ideal coupling agent for facilitating the formation of amide bonds between carboxyl and amine groups. This key functionality is harnessed in peptide synthesis, protein conjugation, and cross-linking applications, aiding in the development of complex bioconjugates and advanced biomaterials.
What sets N-(3-Dimethylaminopropyl)-N''-ethylcarbodiimide apart is its exceptional solubility in water, allowing for easy handling and effective reactions in aqueous environments, which is particularly beneficial when working with sensitive biomolecules. Furthermore, the reagent is known for its minimal side reactions and efficient conversion rates, thus enhancing the purity and yield of the final product.
In research and industrial settings, N-(3-Dimethylaminopropyl)-N''-ethylcarbodiimide is an invaluable tool in the synthesis of oligonucleotides and the immobilization of enzymes, antibodies, and other proteins onto a variety of substrates for diagnostic or analytical purposes. Its versatility and reliability make it a staple in laboratories and production facilities seeking to develop high-performance biological and chemical products.