LEE011 succinate Supplier & Distributor of CAS# 1211441-98-3

LEE011 succinate

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Product Description:

LEE011 succinate is an orally bioavailable small molecule inhibitor of cyclin dependent kinases 4 and 6 (CDK4/6) with potential antineoplastic activity.

Applications & Uses:

CAS#:

1211441-98-3

SYNONYM:

Ribociclib succinate;LEE011 succinate

FORMULA:

C30H35N7O2.C4H6O4

PRODUCT TYPE:

HAZARD:

CATEGORIES:

Pharmaceutical

Technical Specifications

Molecular weight, g/mol :

506.56

LEE011 succinate is a potent, highly selective cyclin-dependent kinase (CDK) inhibitor with a specific affinity for CDK4 and CDK6. It is primarily utilized in cancer research and treatment due to its ability to impede the proliferation of cancer cells by arresting the cell cycle at the G1 phase. This blockade of CDK4/6 function is crucial as these kinases are key regulators of cell cycle progression in cancer cells, making LEE011 succinate an effective agent in targeted cancer therapies, particularly in the treatment of hormone receptor-positive, HER2-negative breast cancer. Its oral bioavailability enhances its practicality for therapeutic uses. By integrating advanced medicinal chemistry, LEE011 succinate is formulated to maximize therapeutic efficacy while minimizing adverse effects, making it a vital component in oncological pharmacotherapy.

Details

CAS #

1211441-98-3

CATEGORIES:

Pharmaceutical

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