Product Description:
Carbenoxolone is a synthetic derivative of glycyrrhetinic acid with anti-inflammatory properties, used primarily for treating ulcers and as a mineralocorticoid receptor antagonist.
Applications & Uses:
CAS#:
5697-56-3
SYNONYM:
Biogastrone;CBX;Carbenoxolone Sodium;Carbenoxolone Disodium Salt
FORMULA:
C34H50O7
PRODUCT TYPE:
HAZARD:
Irritant
CATEGORIES:
Pharmaceutical
,
Research and Development
,
Specialty Chemicals
Technical Specifications
Appearance :
white powder
Melting point, °C :
288-290
Molecular weight, g/mol :
474.62
Carbenoxolone is a synthetic derivative of glycyrrhizic acid, renowned for its diverse applications across the pharmaceutical and research sectors. It is primarily used as an anti-inflammatory agent, leveraging its capacity to inhibit 11β-hydroxysteroid dehydrogenase, thereby modulating the activity of glucocorticoids. This function makes it particularly valuable in investigating processes related to inflammation and corticosteroid pathways.
Additionally, Carbenoxolone is widely recognized for its role in neuroprotection research. It acts as a gap junction blocker, specifically inhibiting connexin channels, which makes it a crucial tool in studies focused on neurodegenerative diseases and neurological damage mitigation strategies. Its ability to influence cellular communication pathways also extends its application to cancer research, where it provides insights into cell proliferation and metastasis.
In gastroenterology, Carbenoxolone has been utilized for its protective effects on gastric mucosa, offering therapeutic potential for conditions such as ulcers and reflux esophagitis. This compound’s versatility makes it an indispensable component in both therapeutic and experimental frameworks, providing expansive opportunities for exploration and innovation in medical science.