Technical Specifications
Appearance :
Colorless liquid
Boiling Point, °C :
82-84
Density, g/cm3 :
0.847
Flash Point, °C :
-6
Melting point, °C :
-60
Molecular weight, g/mol :
104.15
Odor :
Ethereal
Refractive index, n20/D :
1.384
1,2-Dimethoxypropane is a highly efficient and versatile reagent widely used in organic synthesis and chemical industries. This colorless liquid serves as an essential acetal protecting agent for alcohols, especially in the protection of sensitive hydroxyl groups during multi-step synthesis processes. Its effectiveness rises from its ability to form ketal intermediates with acetone and other carbonyl-containing compounds, enabling flexibility and stability in synthesis pathways.
This compound is particularly valuable in the preparation of advanced intermediates and fine chemicals. It plays a crucial role in dehydration processes where it acts as a water scavenger, facilitating the removal of water from reaction environments to drive chemical reactions towards completion. Its properties make it an ideal candidate for the synthesis of pharmaceuticals, agrochemicals, and various specialty chemicals.
In research and development settings, 1,2-dimethoxypropane is prized for its ability to initiate the formation of protective groups on alcohols rapidly, while being easily removable under acidic conditions. The reagent offers ease of handling, high purity, and reliability, making it a staple in modern laboratories focused on innovation in chemical synthesis.